Acupuncture Hpa Axis
The interplay of stress hormones of the hypothalamuspituitaryadrenal axis HPA and the sympathetic nervous system. These organs and their interactions constitute the.
Dysfunction of the hippocampal serotonin 5-hydroxytryptamine 5-HT system has been shown to be a key factor in depression.
Acupuncture hpa axis. Previous animal experiments confirmed that acupuncture is effective in regulating the level of HPA axis-related hormones 32 33 although a limited number of clinical studies have been conducted. The HPA axis-mediated acupuncture inhibition of inflammatory oedema may be involved in the reduction of nasal. In rat models inflammation is experimentally induced and HPA-axis stimulation via acupuncture releases corticosterone which ameliorates the inflammation.
There is growing evidence that electro-acupuncture EA has antidepressant-lik. Previous animal experiments con-firmed that acupuncture is effective in regulating the level of HPA axis-related hormones 32 33 although a limited number of clinical studies have been conducted. The hypothalamus the pituitary gland a pea-shaped structure located below the thalamus and the adrenal also called suprarenal glands small conical organs on top of the kidneys.
The hypothalamicpituitaryadrenal axis HPA axis or HTPA axis is a complex set of direct influences and feedback interactions among three components. Studies have shown that acupuncture helps to regulate the HPA axis thereby correcting problems that arise from adrenal hormone and neurotransmitter derangement like depression anxiety fatigue and insomnia. In the mechanisms of acupuncture analgesia an important aspect often overlooked is the anti-inflammatory effect of acupuncture which is mainly attained through the self-limiting inflammatory response-inflammatory reflex and its regulation of hypothalamic-pituitary-adrenalHPA axis and autonomic nerve system the vagus nerve and the sympathetic postganglionic fiber.
Corticosterone is the primary form of corticosteroids in rats and other non-human animals. In TCM the cause and treatment of illness are based on a holistic understanding of the human body and the HPA axis is a major component of the neuroendocrine system that is critical for maintaining internal homeostasis. However the disruption of the HPA axis has been found to have no effect on the antihyperalgesic effects of acupuncture or electroacupuncture suppression of leucocyte migration in a mouse air pouch inflammation model 4749.
For evidence the review cites two. HPA axis 30 31. However its mechanisms of action in allaying stress remains unclear.
Thus it is reasonable to expect that acupuncture at ST36 modulates the function of the HPA axis during ethanol withdrawal. Hypothalamic-pituitary-adrenal HPA axis has been implicated in the pathogenesis of depression. The claim is that acupuncture stimulates the HPA axis.
A previous study demonstrated that acupuncture at ST36 Zu-San-Li attenuates ethanol-withdrawal EW-induced hyperactivation of the hypothalamicpituitaryadrenal axis HPA axis in rats. Website Design by Mais Oui Creative. 55 The HPA axis hormones in acupuncture-treated rats were unchanged by cold stress remaining similar to that of un-stressed and un-treated controls for 4.
Therefore insomnia is closely associated with dysfunction of the HPA axis 30 31. Acupuncture reduced immune cell levels shifting the hyporesponsiveness of the HPA axis and increasing corticotropin-releasing hormone CRH levels. To that end the second study in this series administered acupuncture immediately following cold stress exposure achieving the same stress hormone preventing effects as the former study.
Many seek out acupuncture to reduce pain treat addictions like smoking and aid with mood disorders among many other reasons. Electroacupuncture EA is used to treat chronic stress. Another asthma acupuncture research study Wei et al utilized manual acupuncture at GV 14 BL 12 and BL 13 to reduce airway inflammation and regulate HPA activity in asthma patients.
Methodsdesign Hypothesis Based on the validity of acupuncture in treating insomnia we hypothesize that acupuncture will. Previous research has proved acupuncture can regulate the function of the neuron-endocrine-immune system and contribute to improving the quality of life of patients. Patients with moderate and severe persistent allergic rhinitis AR have long-term physical and mental stress leading to dysfunction of the hypothalamus-pituitary-adrenal HPA axis which results in recurrence of AR.